Monday, 6 December 2010

Name that stereochemistry

Here's an image from PubChem. I count two chiral centers, but for how many of these is the chirality specified?

3 comments:

  1. Which wedge bond formalism are you using here again?

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  2. That's exactly the issue. The image is a faithful reproduction of the underlying MOL file, but 2D mol files are not very useful without knowing the wedge bond convention adopted. I'll expand in a further blog post.

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  3. This representation would probably cost a point or two on an undergraduate exam. I don't think any formalism, however internally correct, would make it palatable to a practicing chemist.

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